Faculty of the Genetics Program A to Z
Acosta-Martinez, Maricedes, Physiology & Biophysics. Neuroendocrine regulation of the hypothalamus-pituitary-gonad (HPG) axis
Amor Vegas, Corina, Cold Spring Harbor. Cellular senescence and immune surveillance in cancer and aging
Bahou, Wadie, Medicine/Hematology. Genetic disorders of hemostasis and thrombosis
Beyaz, Semir, Cold Spring Harbor. Dietary regulation of immunity and cancer; epigenetics; metabolism
Bialkowska, Agnieszka, Medicine/Gastroenterology and Hepatology. Acute and chronic pancreatitis; pancreatic cancer; animal models; pancreatic stromal and immune cell interactions,;single-cell and bulk next-generation sequencing
Bingham, Paul, Biochemistry & Cell Biology. Novel approaches to cancer chemotherapy; genetic control of development and gene expression in animals
Brownlee, Christopher, Pharmacological Sciences. Molecular mechanisms of spindle orientation, ciliogenesis, polarity, actin cortex formation, and axonogenesis
Canals, Daniel, Medicine and Cancer Center. Lipid signaling and metabolism in cancer
Carpino, Nicholas, Microbiology & Immunology. Positive and negative regulation of T cell receptor signaling
Carter, Carol A., Microbiology & Immunology. Retroviral assembly and post-assembly events
Cheadle, Lucas, Cold Spring Harbor. Neuro-immune mechanisms of brain development and disease
Chen, Jiang, Pathology. Planar cell polarity and primary cilia in skin and hair follicle development and skin cancers
Cheung, Leonard, Physiology & Biophysics. Genetic control of pituitary cell fate throughout life using animal and pluripotent cell models and single-cell technologies
Chung, Jun, Pathology. Mechanisms of tumor invasion and metastasis
Citovsky, Vitaly, Biochemistry & Cell Biology. Genetic transformation, intercellular transport, and chromatin remodeling in plants
Colognato, Holly, Pharmacological Sciences. Extracellular matrix in the brain: roles during development and neurodegeneration
Damaghi, Medhi, Pathology. Tumor evolution in its microenvironment using single-cell multi omics and spatial omics connecting genotype to phenotype
Davalos, Liliana, Ecology & Evolution. Environmental change and its relationship to phylogeny, population genetics, and biodiversity conservation
Del Poeta, Maurizio, Microbiology & Immunology. Sphingolipid metabolism and signaling in fungal and mammalian cells
Demple, Bruce, Pharmacological Sciences. Cellular systems to counteract oxidative damage
Devarajan, Priyadharshini, Microbiology & Immunology. Enhancing lung and nasal immune defense against respiratory viruses; harnessing T cell memory for enhanced protection; bolstering aged immune responses to combat infections; development of vaccines targeting respiratory pathogens
Dobin, Alexander, Cold Spring Harbor. Computational multi-omics; biological big data; bioinformatics tools
dos Santos, Camila, Cold Spring Harbor. Epigenetic dependencies of normal and malignant breast development; gene expression in prevention and treatment of cancer
Dubnau, Josh, Anesthesiology. Learning, memory, genetics, and behavior
Eanes, Walter, Ecology & Evolution. Molecular evolution and phylogenetic analysis
Egeblad, Mikala, Cold Spring Harbor. Tumor microenvironment, tumor-associated myeloid cells, and breast cancer
Enikolopov, Grigori, Anesthesiology. Stem cells, neurogenesis, and signal transduction
Fearon, Douglas, Cold Spring Harbor. Cancer immunology; immunotherapy; host response to cancer
Freimuth, Paul, Brookhaven National Laboratory. Virus-receptor interactions
Frohman, Michael, Pharmacological Sciences. Lipid signaling in normal physiology, diabetes, and cancer
Furie, Martha B., Pathology. Interactions of bacterial pathogens with host cells of innate immunity
Futcher, A. Bruce, Microbiology & Immunology. Cancer, cell cycle, cyclins, microarrays, computational biology, and yeast genetics
Ge, Shaoyu, Neurobiology & Behavior. Functional integration of new neurons into brain circuits
Gergen, J. Peter, Biochemistry & Cell Biology. Transcriptional regulation in Drosophila
Ghebrehiwet, Berhane, Medicine. Structure-function of C1q receptors and their role in infection, inflammation, and cancer
Gingeras, Thomas, Cold Spring Harbor. Genome-wide organization of transcription and functional roles of non-protein coding RNAs
Hammell, Christopher, Cold Spring Harbor. Genetic regulation of temporal development and the function of animal microRNAs
Hammell, Molly, Cold Spring Harbor. Computational and functional genomics; control of transposable elements; neurodegenerative disease
Hannun, Yusuf, Medicine and Cancer Center. Mechanisms and functions of bioactive sphingolipids in cancer
Hu, Chi-Kuo, Bochemistry & Cell Biology. The biology of dormancy and its interaction with development and aging.
Jackson, David, Cold Spring Harbor. Plant development; stem cell signaling; genomics and imaging
Janowitz, Tobias, Cold Spring Harbor. Host response to cancer: metabolic, endocrinological, neurological, and immunological consequences and treatment strategies in cancer medicine
Josephs, Eric, Biomedical Engineering. Molecular engineering of CRISPR systems for applications in personalized gene therapies, diagnostics, and antiviral biotechnologies; molecular mechanisms of viral and bacterial mutation
Joshua-Tor, Leemor, Cold Spring Harbor. Structural biology; nucleic acid regulation; RNAi; molecular recognition; X-ray crystallography
Ju, Jingfang, Pathology. miRNAs in proliferation, cell-cycle control, chemoresistance of tumor stem cells, and epithelial-to-mesenchymal transition
Karzai, A. Wali, Biochemistry & Cell Biology. Structure and function of RNA-binding proteins; SmpB-SsrA quality control system
Kernan, Maurice, Neurobiology & Behavior. Mechanical senses in Drosophila; ciliary signaling
Kim, Hwan, Microbiology & Immunology. Rickettsial pathogenesis and vaccine assembly for tick-borne rickettsioses
Kim, Hyungjin, Pharmacological Sciences. Mechanisms of mammalian DNA replication and repair in cancer development and therapy
Konopka, James, Microbiology & Immunology. Genetic analysis of the fungal pathogen Candida albicans
Koo, Peter, Cold Spring Harbor. Computational biology; artificial intelligence; interpretable deep learning for genomics
Krainer, Adrian R., Cold Spring Harbor. Posttranscriptional control of gene expression; pre-mRNA splicing mechanisms, fidelity and genetic diseases
Kritzer, Mary, Neurobiology & Behavior. Effects of the gonadal hormones on the structure, biochemistry, and function of the cerebral cortex
Li, Bo, Cold Spring Harbor, Neuroscience. Glutamatergic synapses; synaptic plasticity; schizophrenia; depression; rodent models of psychiatric disorders
Lin, Richard, Physiology & Biophysics. Physiological functions and pathological roles of phosphoinositide 3-kinases (PI3Ks)
Luberto, Chiara, Physiology & Biophysics. Sphingolipid metabolism and signaling
Luk, Ed, Biochemistry & Cell Biology. Cellular organization of chromatin structure for accommodation and control of gene expression
Lukey, Michael, Cold Spring Harbor. Metabolic reprogramming during tumorigenesis and metastasis
Mackow, Erich, Microbiology & Immunology. Rotavirus and hantavirus genetics and pathogenesis
Martienssen, Robert, Cold Spring Harbor. Epigenetics; chromatin and chromosome biology; stem cells; plant genomics; plant evolution; aquatic plants
Martin, Benjamin, Biochemistry & Cell Biology. Stem cell maintenance and differentiation; developmental mechanisms of cancer pathogenesis
Martinez, Luis, Pathology. Gain of function of mutant p53 oncogene
McCombie, Richard, Cold Spring Harbor. Genomics of psychiatric disorders; genomics of cancer; computational genomics; plant genomics
Meyer, Hannah, Cold Spring Harbor. Tolerance induction and generation of diversity in the developing immune system; systems immunology; transcriptomics; bioinformatics
Mills, Alea, Cold Spring Harbor. Cancer; development; aging; senescence; epigenetics; autism
Misra, Jyoti, Pharmacological Sciences. Regulation of growth in development and cancer by Hippo signaling
Moll, Ute, Pathology. The p53/p73/p63 gene family in human cancer; transcription-independent mitochondrial apoptosis program of p53
Neiman, Aaron, Biochemistry & Cell Biology. Vesicle trafficking and membrane-cytoskeletal interactions
Nelson, Jonathan, Biochemistry & Cell Biology. Understanding the impact of retrotransposons and repetitive DNA maintenance in germline genome stability
Pedmale, Ullas, Cold Spring Harbor. Organism-environment interactions; photobiology; signal transduction; genomics; cellular growth; decision-making in plants
Pisconti, Dada, Biochemistry & Cell Biology. Muscle stem cells; muscular dystrophy; muscle development; muscle regeneration; muscle aging; extracellular matrix; biology of proteoglycans
Powers, R. Scott, Pathology. Cancer gene discovery; cancer diagnostics and therapeutics; cancer biology
Rahme, Gilbert, Pharmacological Sciences. Cancer epigenetics with a focus on brain tumors
Reich (Marshall), Nancy, Microbiology & Immunology. Signaling switches in gene expression by hormones or viral infection
Rest, Joshua, Ecology & Evolution. Computational, comparative, and experimental approaches to study linkage of genotype and phenotype
Schorn, Andrea, Cold Spring Harbor. Non-coding and small RNA; transposable elements; stem cells; epigenetics
Seeliger, Jessica, Pharmacological Sciences. Mechanisms of cell wall and membrane assembly in Mycobacterium tuberculosis
Seeliger, Markus, Pharmacological Sciences. Molecular mechanisms of protein kinase and ubiquitin ligase signaling in cancer and aging
Shelly, Maya, Neurobiology & Behavior. Molecular mechanisms of embryonic brain development; axon regeneration; neurodegenerative disorders
Sher, Roger, Neurobiology & Behavior. Neurobiology; neurodegenerative diseases; amyotrophic lateral sclerosis; Alzheimer's; dementias
Sheridan, Brian, Microbiology & Immunology. Mucosal immunology; T cell memory; vaccine design; host-pathogen interactions
Shields, Mario, Pathology. Mechanisms of development and progression of pancreatitis and pancreatic cancer; tissue homeostasis; G-protein signaling; tumor inflammation and metabolism
Shroyer, Kenneth, Pathology. Molecular characterization of benign, premalignant, and malignant lesions of the female genital tract
Siepel, Adam, Cold Spring Harbor. Computational biology; population genetics; computational genomics; molecular evolution; transcriptional regulation
Sirotkin, Howard, Neurobiology & Behavior. Genetic and environmental regulation of neurogenesis; neurological disorders including autism and epilepsy
Spector, David, Cold Spring Harbor. Cell biology; gene expression; nuclear structure; non-coding RNAs
Stillman, Bruce, Cold Spring Harbor. Cancer; cell cycle; DNA replication; chromatin assembly; biochemistry; yeast genetics
Takemaru, Ken-Ichi, Pharmacological Sciences. Cell signaling and ciliogenesis in mammalian development, health, and disease
Talos, Flaminia, Urology/Pathology. Intra-tumor heterogeneity in prostate cancer; tissue reprogramming in the urinary bladder
Tan, Dongyan, Pharmacological Sciences. Epigenetics, chromatin structure and function in transcription and DNA damage repair
Thanassi, David, Microbiology & Immunology. Secretion of bacterial virulence factors and their roles in pathogenesis
Thomsen, Gerald, Biochemistry & Cell Biology. The transforming growth factor-ß family in embryonic development
Tollkuhn, Jessica, Cold Spring Harbor. Regulation of gene expression in the brain by estrogen and testosterone
Tonks, Nicholas, Cold Spring Harbor. Posttranslational modification; phosphorylation; phosphatases; signal transduction; protein structure and function
Trotman, Lloyd, Cold Spring Harbor. Animal models for metastatic cancer therapy and analysis; 3D organ imaging; diet and oxidative cell death mechanisms; the cancer-neuro interface
Tuveson, David, Cold Spring Harbor. Pancreatic cancer; experimental therapeutics; diagnostics; mouse models; cancer genetics
Vakoc, Christopher, Cold Spring Harbor. Transcriptional regulation of mammalian cell growth
Van Aelst, Linda, Cold Spring Harbor. Signal transduction; Ras and Rho proteins; tumorigenesis; neuronal development
Van der Velden, Adrianus, Microbiology & Immunology. The mammalian T cell response to Salmonella enterica serovar Typhimurium
Veeramah, Krishna, Ecology & Evolution. Evolutionary genomics
Wan, Ledong, Pharmacological Sciences. RNA metabolism; inflammation; cancer
Weissman, Jackie Lee, Ecology & Evolution. Metagenomics and comparative genomics; microbial ecology and evolution; bioinformatics; computational biology
Westcott, Peter, Cold Spring Harbor. Cancer genomics and immunology; evolution of immune surveillance and dysfunction during cancer progression and metastasis
White, Thomas, Physiology & Biophysics. Gap junction functions defined by genetic diseases and gene knockouts
Williams, Jennie, Family, Population and Preventive Medicine. Cancer chemotherapeutics; cancer health disparity; tumor biology; chemoresistance/chemoresponse in racial and ethnic populations
Zachar, Zuzana, Biochemistry & Cell Biology. Cancer chemotherapy drug discovery
Zhan, Huichun, Medicine/Hematology. The intersection of clonal hematopoiesis, bone marrow immune microenvironment, and cardiovascular diseases
Zhang, Lingbo, Cold Spring Harbor. Normal and malignant stem and progenitor cells; self-renewal; metabolism; therapeutic targets